It begins to reach the fluid within a dog’s joints within 2 hours and detectable levels are maintained in the fluid and
cartilage for up to 3 days (72 hours).1 Talk to your veterinarian if you have additional questions.
Many joint supplements and pain relievers like non-steroidal anti-inflammatory drugs (NSAIDs) are labeled for daily use and the cost can add up over time.
Adequan Canine is administered as a series of 8 doses over the course of 4 weeks. The series may be repeated as needed during your dog’s lifetime.
While the initial up-front cost may seem higher for Adequan Canine, it doesn’t need to be administered daily or monthly, so over the course of your dog’s life it
can actually be less expensive than daily supplements or pain medications.
Using Adequan Canine early, when your dog first shows warning signs of joint damage, may help slow the progression of arthritis before the joint cartilage wears away for good. Adequan Canine is the only FDA-approved treatment that inhibits cartilage loss in a dog’s synovial joints, and
may help to restore joint lubrication, relieve inflammation, and renew the building blocks of healthy cartilage.2
By administering Adequan Canine twice weekly for up to 4 weeks (maximum of 8 injections), the drug levels are sustained in the synovial joints for an extended period of time—giving the active ingredients time in the joint to
help slow the progression of arthritis. The specific mechanism of action of Adequan® in canine joints is not known.
This subsequent series of injections are called "maintenance" because they help protect your dog’s joint health after the initial series of injections with Adequan Canine. If your dog is stiff,
limping or has other symptoms of arthritis again, your veterinarian will likely repeat the dosing regimen to help get your dog back on track.
Contact your veterinarian to discuss and confirm their guidance and direction.
Adequan® Canine should not be used in dogs who are hypersensitive to polysulfated glycosaminoglycan (PSGAG) or who have a known or suspected bleeding disorder.
It should be used with caution in dogs with renal or hepatic impairment. Adverse reactions in clinical studies (transient pain at injection site, transient diarrhea,
and abnormal bleeding) were mild and self-limiting. In post approval experience, death has been reported in some cases; vomiting, anorexia, depression/ lethargy and
diarrhea have also been reported. The safe use of PSGAG in breeding, pregnant or lactating dogs has not been evaluated.
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. For additional safety information, please see the
Full Prescribing Information.
For specific questions about your dog’s treatment plan, talk to your veterinarian. They will be able to provide more detailed answers based on your dog’s history and diagnosis with arthritis.
If you would like to speak to an American Regent Animal Health customer service representative, call 800-458-0163 Monday-Thursday from 8:30 a.m. – 6 p.m. ET or Friday from 8:30 a.m. – 5 p.m. ET.
Adequan Canine is a prescription-only product and can only be purchased through a licensed, practicing veterinarian or from a pharmacy with a valid prescription.
Contact us or explore the information on this site.
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*Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian.